Urticarial vasculitis - Vasculitis Urticarial
☆ Ninu awọn abajade 2022 Stiftung Warentest lati Jẹmánì, itẹlọrun alabara pẹlu ModelDerm jẹ kekere diẹ ju pẹlu awọn ijumọsọrọ telemedicine isanwo.
References
Urticarial vasculitis jẹ ipo ti o ṣọwọn ti a samisi nipasẹ awọn iṣẹlẹ pipẹ tabi loorekoore ti hives. Lakoko ti awọn aami aiṣan awọ ara rẹ le dabi awọn hives onibaje, wọn jẹ alailẹgbẹ nitori awọn hives duro ni ayika fun o kere ju wakati 24 ati pe o le fa awọn aaye dudu lẹhin ti o rọ. Botilẹjẹpe igbagbogbo idi ti a ko mọ, o le ma nfa nipasẹ awọn oogun kan, awọn akoran, awọn arun autoimmune, awọn rudurudu ẹjẹ, tabi awọn aarun. Diẹ ninu awọn ijinlẹ paapaa ti sopọ mọ COVID-19 ati aisan H1N1. O tun le kan awọn ẹya ara miiran bi awọn iṣan, awọn kidinrin, ẹdọforo, ikun, ati oju. Lakoko ti iru idanwo ara kan le jẹrisi ayẹwo, kii ṣe pataki nigbagbogbo. Itọju maa n bẹrẹ pẹlu awọn oogun aporo, dapsone, colchicine, tabi hydroxychloroquine fun awọn ọran kekere. Fun awọn ọran ti o nira diẹ sii, awọn oogun ti o dinku eto ajẹsara bi methotrexate tabi corticosteroids le nilo. Laipe, awọn itọju ailera (rituximab, omalizumab, interleukin-1 inhibitors) ti ṣe afihan ileri fun awọn ọran lile.
Urticarial vasculitis is a rare clinicopathologic entity that is characterized by chronic or recurrent episodes of urticarial lesions. Skin findings of this disease can be difficult to distinguish visually from those of chronic idiopathic urticaria but are unique in that individual lesions persist for ≥24 hours and can leave behind dusky hyperpigmentation. This disease is most often idiopathic but has been linked to certain drugs, infections, autoimmune connective disease, myelodysplastic disorders, and malignancies. More recently, some authors have reported associations between urticarial vasculitis and COVID-19, as well as influenza A/H1N1 infection. Urticarial vasculitis can extend systemically as well, most often affecting the musculoskeletal, renal, pulmonary, gastrointestinal, and ocular systems. Features of leukocytoclastic vasculitis seen on histopathologic examination are diagnostic of this disease, but not always seen. In practice, antibiotics, dapsone, colchicine, and hydroxychloroquine are popular first-line therapies, especially for mild cutaneous disease. In more severe cases, immunosuppressives, including methotrexate, mycophenolate mofetil, azathioprine, and cyclosporine, as well as corticosteroids, may be necessary for control. More recently, select biologic therapies, including rituximab, omalizumab, and interleukin-1 inhibitors have shown promise for the treatment of recalcitrant or refractory cases.
Urticarial vasculitis is a rare clinicopathologic entity that is characterized by chronic or recurrent episodes of urticarial lesions. Skin findings of this disease can be difficult to distinguish visually from those of chronic idiopathic urticaria but are unique in that individual lesions persist for ≥24 hours and can leave behind dusky hyperpigmentation. This disease is most often idiopathic but has been linked to certain drugs, infections, autoimmune connective disease, myelodysplastic disorders, and malignancies. More recently, some authors have reported associations between urticarial vasculitis and COVID-19, as well as influenza A/H1N1 infection. Urticarial vasculitis can extend systemically as well, most often affecting the musculoskeletal, renal, pulmonary, gastrointestinal, and ocular systems. Features of leukocytoclastic vasculitis seen on histopathologic examination are diagnostic of this disease, but not always seen. In practice, antibiotics, dapsone, colchicine, and hydroxychloroquine are popular first-line therapies, especially for mild cutaneous disease. In more severe cases, immunosuppressives, including methotrexate, mycophenolate mofetil, azathioprine, and cyclosporine, as well as corticosteroids, may be necessary for control. More recently, select biologic therapies, including rituximab, omalizumab, and interleukin-1 inhibitors have shown promise for the treatment of recalcitrant or refractory cases.
Ọkunrin 35 kan ti o jẹ ọdun 35 wa pẹlu itan-ọjọ 15 ti o ni awọ pupa ti o ni imọlẹ, irora irora lori itan ati awọn ẹsẹ mejeeji, pẹlu irora apapọ. O ni ikolu ito fun ọsẹ kan ṣaaju ki o to han. Awọ ara rẹ ṣe afihan pupọ tutu, ti o ni iwọn oruka, ti o le ni apakan kan, awọn ami-ami pupa ni ẹgbẹ mejeeji ti itan ati awọn ẹsẹ rẹ. A fun ni prednisolone oral (40mg / ọjọ) fun ọsẹ kan pẹlu antihistamine ti kii-drowsy (fexofenadine) . Laarin ọsẹ kan, gbogbo awọn rashes farasin patapata. Ko si awọn rashes diẹ sii ni awọn oṣu 6 to nbọ ti awọn iṣayẹwo deede.
A 35-year-old man came in with a 15-day history of bright red, painful rashes on both thighs and legs, along with joint pain. He had a urinary tract infection for a week before the rash appeared. His skin showed several tender, ring-shaped, partially blanchable, red plaques on both sides of his thighs and legs. He was given oral prednisolone (40mg/day) for a week along with a non-drowsy antihistamine (fexofenadine). Within a week, all the rashes disappeared completely. There were no more rashes during the next 6 months of regular check-ups.
A 35-year-old man came in with a 15-day history of bright red, painful rashes on both thighs and legs, along with joint pain. He had a urinary tract infection for a week before the rash appeared. His skin showed several tender, ring-shaped, partially blanchable, red plaques on both sides of his thighs and legs. He was given oral prednisolone (40mg/day) for a week along with a non-drowsy antihistamine (fexofenadine). Within a week, all the rashes disappeared completely. There were no more rashes during the next 6 months of regular check-ups.
○ Itọju - Oògùn OTC
Ti o ba ni iba (iwọn otutu ara ti o pọ si), a ṣeduro pe ki o wa itọju ilera ni kete bi o ti ṣee.
Oogun ti a fura si yẹ ki o dawọ duro. (fun apẹẹrẹ, awọn egboogi, awọn oogun egboogi-iredodo ti kii ṣe sitẹriọdu)
Awọn antihistamines ti ẹnu bi cetirizine tabi loratadine fun nyún.
#Cetirizine [Zytec]
#LevoCetirizine [Xyzal]
#Loratadine [Claritin]
Awọn ikunra sitẹriọdu OTC le jẹ alailagbara fun agbara kekere. Nilo lati lo fun diẹ ẹ sii ju ọsẹ kan lati rii ilọsiwaju.
#Hydrocortisone ointment